An article by Dr. Martin Pall discusses how the effects of post radiation syndrome mimicked the symptoms of chronic fatigue syndrome. He believes that this provides more evidence to support his NO/ONOO(-) cycle theory of chronic fatigue.
In this theory, inducible nitric oxide is increased in the body by any number of different reasons (viral infection, stress, chemical exposure).
A new study about the brain blood flow and oxygenation in chronic fatigue patients confirms what i’ve seen in my own lab tests and brain scans.
This CFS study
shows that chronic fatigue syndrome patients had reduced oxygenation and brain blood flow after exercise. Their total blood volume and oxygen levels were significantly reduced in the prefrontal areas, when compared to control subjects.
A previous study out of Italy also shows altered brain bloodflow and metabolism in CFS patients when compared to healthy and depressed subjects.
Vitamin D deficiency is believed to be involved in many types of diseases including osteoporosis, rickets, diabetes, and high blood pressure. It has been common knowledge for years that vitamin D supplementation can help treat certain diseases and is overall benefical to one’s health.
But, one doctor is questioning that idea.
An Australian doctor named Trevor Marshall believes that vitamin D intake may lower the immune system’s ability to fight infection.
A symptom that i have a big problem with, but i haven’t heard much talk about is the vision problems that came with my chronic fatigue. I have constant blurred vision that improves when i feel better. I see spots that i would describe as similar to when you feel light headed or faint. At one point it was so bad that had trouble reading and driving.
One of things that helps me with this symptom, is the systemic enzyme complex vitalzyme. This clears my vision along with helping with my brain fog. I’m guessing this enzyme complex works for me because it thins the blood and may
On July 8th Ampligen’s NDA was accepted for review by the FDA.
So what exactly does that mean, and how much further in the process toward approval is it?
“NDA” stands for new drug application.
Recently a study was conducted in the UK that showed a problem with an overactive negative hpa axis feedback loop in chronic 
fatigue patients. The UK researchers used dexamethasone to observe changes to the feedback loop over 6 hours. The drug dexamethasone is a glucocorticoid similar to cortisol. If a person takes dexamethasone their body should make less ACTH (a hormone that causes the release of cortisol). In normal people the amount of ACTH and cortisol should fall to a certain range.
The CFS patients in the study had lower than normal levels of cortisol and ATCH after the dexamethasone test.
Ive always had a favorable response to B12. It improves all of my symptoms, especially brain fog. I finally got to try my first Hydroxocobalamin B12 shot (after having to convince my Dr.) and within a couple hours my brain fog feels much improved. My genetic test results from amy yasko showed that i have a mutation in the gene MTRR that recycles b12.
So these shots may be very beneficial me.
From what i have read, b12 is very helpful to most cfs patients. The reasons that it might help is that b12 is a scavanger for the free radicals nitric oxide and peroxynitrite. Nitric oxide can caused decreased barin fuction and also can
Cymbalta is an antidepressant that blocks the reuptake of serotonin and noradrenaline. It was first used to treat depression, but also may help to reduce chronic pain. This week is was approved to treat fibromyalgia, but has been prescribed off label to FMS patients for a while now.
A paper out of the university of San Francisco says that noradrenaline is a key component in inhibiting pain. They have found that low levels of noradrenaline make the use of opiates less effective.
There is no shortage of theories about CFS. Doctors like Amy Yasko and Rich Van Konyenberg, believe that chronic fatigue patients may have defects in their methylation cycle. Six months ago i had a genetic test done to see how my methylation cycle was functioning.
My test results showed that i had a defect in sulfur metabolism. The gene SUOX S370S was +/-. I believe this means that my body converts sulfites into sulfates very quickly. And it may lead to a buildup of sulfates which are removed from the body by B12 and molybdenum.
A recent study shows that like Ritalin may improve cognitive function in CFS patients. This small study showed that there were positive results in concentration and memory when using immediate release methylphenidate (Ritalin).
Other stimulants like Provigil have also been used in CFS patients to improve symptoms. Provigil is most often used with diseases like narcolepsy and ADHD. This drug works by affecting the chemical glutamate and can have less side effects than other stimulants.
I have personally tried Ritalin, Adderall, and Provigil. Even though some people with CFS had improvements, for me they were very overstimulating. I didnt feel much improvement in cognitive function or memory. I also had alot of side effects, like insomnia, loss of appetite, and nervousness.
