D-Ribose is a sugar (derived from glucose) that has been shown to boost levels of the energy compound ATP. Some studies have shown that CFS patients have lower than normal levels of ATP and D-Ribose could be used to increase energy production in the muscles and heart.
The increased levels of ATP may help relieve fatigue by provide the muscles with extra energy. D-Ribose also helps the body to recycle ATP, and use its own energy it has more efficiently.
A study by well know chronic fatigue specialist Dr. Jacob Teitelbaum, has shown D-ribose to improve sleep, fatigue, concentration, pain and well-being in patients.
- There were 36 patients in this study
- The average age of the participants was 48 and was 78% female.
- The patients in this study took D-Ribose at a dose of 5 grams, three times each day.
- 69% of the 36 patients had significant improvement. They had 25% improvement in the quality of life, as compared to before the study.
Ribose has also been used in sports to enhance athletic ability. It can also be used to treat a genetic disorder called myoadenylate deaminase deficiency. In this disorder, a sufferer is deficient in an enzyme called AMP deaminase. A deficient person can have symptoms like energy problems and muscle cramping.
How is D-Ribose Ingested?
This substance can be taken in powder form and mixed into liquid like juice or water. It also can be given intravenously.
The dosages doctors recommend can vary greatly. To enhance performance for athletics some have advised 5 grams daily. But for other medical issues like CFS or heart failure, some doctors have recommended 15-30 grams per day. Speak with your doctor before ingesting any supplements, including ribose.
Other Supplements That May Increase ATP
One supplement that may increase ATP is the antioxidant CoQ10. It is required by all cells to produce ATP inside the mitochondria. CoQ10 may be beneficial to people with certain medical conditions like heart failure. ATP is in very high demand in certain organs like the heart, so supplementation with ribose or CoQ10 has been shown to been helpful in improving “ischemic threshold” and enhancing “diastolic function” in certain studies.
Can this Supplement Increase Blood Sugar?
This substance is a sugar, so diabetics should be wary of how it can affect their bodies. There currently have not been any studies done on blood sugar and d-ribose, so it’s effect are not completely known.
The effectiveness of this supplement on patients with chronic fatigue syndrome seem to be mixed. Some have noticed improvement, while others notice no effect or jitteriness. It does not seem like this is the answer that CFS patients have been looking for, but it may provide some relief of symptoms like low energy.
Try our Sublingual Methyl B12 here, if you are looking to improve energy levels and concentration. It is one of the most effective supplements for CFS that we have seen, it is by no means a cure, but can help some symptoms.