Systemic enzyme supplements have many benefits for chronic fatigue patients. They can improve blood flow by removing fibrin (protein involved in blood clotting) from the blood, reduce inflammation, and help digest food.
Certain doctors like Dr. David Berg believe that CFS patients are in a hypercoagulable state. And that people with CFS and FMS have a genetic predisposition towards a hypercoagulable state. So, a reduction in coagulation by the use of systemic enzymes could help improve blood flow.
In a study from 1998, 16 CFS and FMS patients were given daily injections of Heparin (a blood thinning drug). 8 of these patients experienced significant improvement, and 7 experienced moderate improvement. So, increasing blood flow by thinning the blood, may lead to a reduction in symptoms.
Systemic enzymes are one of the supplements that helps my brain fog the most. If im feeling bad on a particular day, i just take an extra enzyme pill and that helps to relieve my brain fog for the day. The enzyme supplement that i take is called vitalzym. It contains the enzymes: protease, serrapeptase, papain, bromelain, amylase, lipase, rutin, and amla.
I first heard about these in Brian Rosner’s “10 Top Treatments for Lyme”, systemic enzymes made the top 10. He specifically recommended Wobenzyme, which is studied and used more in Germany. As with any other non-synthetic product, there’s little research in the US because of limited profitability. Rosner suggested that it helps particularly in lyme by getting rid of “circulating immune complexes”, which may have an antibiotic effect. I plan to try them sometime, it seems to me like a promising area, especially if there turns out to be a strong connection between coagulation and inflammation (http://www.circ.ahajournals.org/cgi/content/full/109/22/2698)