Using large doses of Vitamin C as a treatment for chronic fatigue syndrome is not a new idea. A doctor named Jay Goldstein had been giving massive doses of Vitamin C to cfs patients for years. He told me that many CFS patients did have a beneficial response to high doses of Vitamin C through an I.V., and i have read other reports of some improvement with high doses.
Vitamin C is well known to help boost the immune system and reduce states of fatigue. So, i think it might be likely to give benefits to CFS patients. Some doctors feel that CFS is at least in part, a free radical induced illness. Energy producing mitochondria create free radicals as a part of energy production. When ATP is generated by the mitochondria, these free radicals are also created as a waste product. If the mitochondria are exposed to excess amount of free radicals, it will produce ATP less efficiently, and fatigue will set in. Vitamin C helps here by donating an electron and destroying the free radical.
Here is a link that shows IV Vitamin C my have a beneficial effect on cancer patients. IN CFS/FMS patients it is possible that IV vitamin C administration could help out with viral/bacterial infections that may be involved with cfs as well as reducing free radical loads. It could also help in the synthesis of certain neurotransmitters like norepinephine and serotonin. Which if low could cause low energy, or depressed mood.
High doses of Vitamin C and other anti-oxidants can help to reduce the free radical load off of the mitochondria. In an article by Dr. Martin Pall, he suggests a theory that CFS is induced by the overproduction of the free-radicals nitric oxide and peroxynitrite. He suggests a combination of the anti-oxidants CoQ-10, Flavinox, NAC, Fish Oil, and a Multimineral with acetyl-l-carnitine and alpha lipoic acid.
If you want to to naturally boost you levels or vitamin c, here is a list of foods that contain the highest levels.
Vitamin C Foods:
- Citrus Fruits
- Bell Peppers
There is an extremely low risk for toxicity of Vitamin C at any level, although high doses can cause diahrrea. It is very safe, but before adding high dose vitamin c to you supplement regimen, you should check with your doctor.
While i dont think that high doses of vitamin C will cure CFS/FMS patients, i do think that IV or high dose Vitamin C could provide relief of symptoms for some patients.